Adoption of light emitting diodes (LEDs) has the potential to revolutionize the controlled environment agriculture (CEA) industry. However, LEDs comprise only an estimated 2% of lit greenhouse area in the U.S. The Greenhouse Lighting and Systems Engineering (GLASE) consortium is a public-private partnership with a goal to reduce horticultural lighting energy consumption by 70% vs. 2014 levels. GLASE research includes testing and adoption of energy efficient LEDs, control algorithms that complement natural light and CO2 availability, and innovations in spectral control. Dr. Mattson will discuss GLASE research optimizing tomato and strawberry production with light and carbon dioxide control, improving light spectral distribution, and use of LEDs to enhance lettuce biomass efficacy (g of edible biomass per kWh electricity). Energy modeling highlighting the impact of LED adoption on greenhouse and vertical farm production will also be presented.